![]() ![]() Polypharmacy increases the risk of adverse drug events and this sometimes causes a sudden and unexpected death. Some of the celebrity deaths were caused by inappropriate use of prescription medications, mostly combined influences of one or more benzodiazepine together with an opiate or opioid pain medication. The illicit drugs mainly responsible for the fatalities were heroin and/or cocaine or a mixture of the two narcotics. The tragic drug-related death of Anna Nicole Smith, a sex-symbol and Playboy model, is also included. ![]() The musicians are exemplified by Elvis Presley, Janis Joplin, Jimi Hendrix, Keith Moon, Sid Vicious, Kurt Cobain, Amy Winehouse, Michael Jackson, Whitney Houston and Prince. The movie stars included: Marilyn Monroe, River Phoenix, John Belushi, Chris Penn, Heath Ledger and Philip Seymour Hoffman. This article presents a review of medicolegal investigations of drug-related deaths among various Hollywood celebrities and popular music icons. ![]()
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